The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Nov. 16, 2017
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Robert Jack Gillespie, Basel, CH;

Hasane Ratni, Habsheim, FR;

Jerome Charles Sarie, Basel, CH;

Assignee:

HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/22 (2006.01); A61K 31/519 (2006.01); C07D 519/00 (2006.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/519 (2013.01); A61P 21/00 (2018.01); C07D 487/22 (2013.01);
Abstract

The present invention provides compounds of formula (I) wherein A, X, Y, Rand Rare as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.


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