The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2019
Filed:
Sep. 23, 2015
Jiaqiang Cai, Shanghai, CN;
Alejandro Crespo, Edison, NJ (US);
John Debenham, Scotch Plains, NJ (US);
Xiaoxing Du, Shanghai, CN;
Ping Liu, Westfield, NJ (US);
Rongqiang Liu, Shanghai, CN;
Christina B. Madsen-duggan, Scotch Plains, NJ (US);
Weiguo Quan, Shanghai, CN;
Christopher Sinz, Middletown, NJ (US);
Liping Wang, Cranbury, NJ (US);
Jiaqiang Cai, Shanghai, CN;
Alejandro Crespo, Edison, NJ (US);
John Debenham, Scotch Plains, NJ (US);
Xiaoxing Du, Shanghai, CN;
Ping Liu, Westfield, NJ (US);
Rongqiang Liu, Shanghai, CN;
Christina B. Madsen-Duggan, Scotch Plains, NJ (US);
Weiguo Quan, Shanghai, CN;
Christopher Sinz, Middletown, NJ (US);
Liping Wang, Cranbury, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention concerns compounds of formula I or a pharmaceutically acceptable salt thereof which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.