The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2019
Filed:
Dec. 24, 2015
Applicant:
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Inventors:
Assignee:
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 471/04 (2006.01); C07D 401/14 (2006.01); A61K 31/4709 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4709 (2013.01); A61K 31/517 (2013.01); A61K 31/55 (2013.01); C07D 401/14 (2013.01);
Abstract
A compound represented by general formula (I) and having a quinoline skeleton has a strong Axl inhibitory activity, and therefore the compound can be an agent for treating Axl-related diseases, for example, cancer such as acute myeloid leukemia, chronic myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.