The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Jan. 11, 2018
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Amanda Elaine Brooks, South Jordan, UT (US);

David W. Grainger, Salt Lake City, UT (US);

Kristofer D. Sinclair, Salt Lake City, UT (US);

Benjamin Delbert Brooks, South Jordan, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/32 (2015.01); A61K 9/52 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61L 27/30 (2006.01); A61L 27/36 (2006.01); A61K 31/7036 (2006.01); A61L 27/26 (2006.01); B05D 3/00 (2006.01); B29C 67/24 (2006.01); B29K 1/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/58 (2013.01); A61K 31/7036 (2013.01); A61L 27/26 (2013.01); A61L 27/306 (2013.01); A61L 27/3608 (2013.01); A61L 27/54 (2013.01); B05D 3/002 (2013.01); B29C 67/24 (2013.01); A61L 2300/406 (2013.01); A61L 2300/412 (2013.01); A61L 2300/62 (2013.01); A61L 2430/02 (2013.01); A61L 2430/24 (2013.01); B05D 2203/00 (2013.01); B29K 2001/08 (2013.01); B29L 2031/7532 (2013.01);
Abstract

In one aspect, the invention provides an implantable device comprising a uniform mixture of components including degradable polymer, inorganic bone particulate either natural or synthetic, a drug, and a soluble microporagen. In some embodiments, the uniform mixture further includes a soluble polymer macroporagen. In some embodiments, the uniform mixture is coated with an immobilized outer porous layer comprising or consisting of synthetic or natural inorganic bone granules. In further aspects, the invention provides an implantable device comprising a composite core of degradable polymer, bone, and a drug, and a coating comprising or consisting of microporous bone overlayer covering the degradable composite core.


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