The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Mar. 29, 2016
Applicant:

Mor Research Applications Ltd., Tel Aviv, IL;

Inventors:

Ayala Pollack, Rehovot, IL;

Zeev Dvashi, Kiryat Ono, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/335 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 31/335 (2013.01); C07K 16/40 (2013.01);
Abstract

Disclosed herein are methods for treatment for fibrosis, ocular pathologies associated with fibrosis, including proliferative vitreoretinopathy (PVR) by inhibiting the activity of activated transforming growth factor β activated kinase 1 (TAK1), or activation thereof. Pharmaceutical compositions for use in the described treatments are also provided.


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