The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Apr. 22, 2015
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Tao Jin, Pittsburgh, PA (US);
Seong-Gi Kim, Pittsburgh, PA (US);
Hunter S. Mehrens, Pittsburgh, PA (US);
Kristy S. Hendrich, Pittsburgh, PA (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Abstract
A method of monitoring glucose transport and/or metabolism in a tissue or an organ of a subject using spin-locking magnetic resonance (MR) includes acquiring pre-glucose MR data by executing a pre-glucose chemical exchange spin-lock (CESL) pulse sequence a number of times each including applying pre-glucose chemical exchange spin-lock pulse sequence irradiation to the tissue or the organ, administering glucose to the subject, acquiring post-glucose MR data by executing a post-glucose chemical exchange spin-lock (CESL) pulse sequence a number of times each including applying post-glucose chemical exchange spin-lock (CESL) pulse sequence irradiation to the tissue or the organ, and using the pre-glucose MR data and the post-glucose MR data to generate a measure of glucose transport, glucose metabolism or both glucose transport and glucose metabolism in the tissue or the organ.