The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Aug. 02, 2012
Applicants:

Jason C. Reed, Los Angeles, CA (US);

Michael A. Teitell, Tarzana, CA (US);

Inventors:

Jason C. Reed, Los Angeles, CA (US);

Michael A. Teitell, Tarzana, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01B 11/06 (2006.01); G01B 9/02 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); G01B 9/0209 (2013.01); G01B 9/02057 (2013.01); G01B 9/02089 (2013.01); G01B 11/0675 (2013.01); G01N 33/502 (2013.01); G01N 33/5026 (2013.01);
Abstract

A central question in cancer therapy is how individual cells within a population of tumor cells respond to drugs designed to arrest their growth. However, the absolute growth of cells, their change in physical mass, whether cancerous or physiologic, is difficult to measure directly with traditional techniques. Embodiments of the invention provide live cell interferometry (LCI) for rapid, realtime quantification of cell mass in cells exposed to a changing environment. Overall, LCI provides a conceptual advance for assessing cell populations to identify, monitor, and measure single cell responses, such as to therapeutic drugs.


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