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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10203330 B1

PDFFull Text
Date of Patent:
Feb. 12, 2019

Filed:

Mar. 10, 2017

Methods and materials for identifying and treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation

Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Farhad Kosari, Ellsworth, WI (US);

George Vasmatzis, Oronoco, MN (US);

Marie-Christine Aubry, Pine Island, MN (US);

Cristiane M. Ida, Rochester, MN (US);

Assignee:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Attorney:

Fish & Richardson, P.C.

Primary Examiner:

Scott Long

Assistant Examiner:

Paul C Martin

Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); A61K 31/13 (2006.01); A61K 31/198 (2006.01); A61K 31/225 (2006.01); A61K 31/26 (2006.01); A61K 31/404 (2006.01); A61K 31/428 (2006.01); A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/5025 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/7135 (2006.01); A61K 38/48 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); A61K 31/13 (2013.01); A61K 31/198 (2013.01); A61K 31/225 (2013.01); A61K 31/26 (2013.01); A61K 31/404 (2013.01); A61K 31/428 (2013.01); A61K 31/44 (2013.01); A61K 31/4439 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 31/517 (2013.01); A61K 31/7135 (2013.01); A61K 38/482 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/158 (2013.01); C12Y 304/21 (2013.01); C12Y 304/21007 (2013.01); C12Y 304/21068 (2013.01); G01N 2333/4703 (2013.01); G01N 2333/71 (2013.01);
Abstract

This document provides methods and materials involved in identifying mammals having lung adenocarcinoma characterized by neuroendocrine differentiation as well as methods and materials involved in treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation. For example, methods and materials for using ASCL1 and RET expression levels to identify lung cancer patients having lung adenocarcinoma characterized by neuroendocrine differentiation are provided.

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