The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Jun. 03, 2015
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Daojing Wang, Moraga, CA (US);

Pan Mao, Fremont, CA (US);

Rafael Gomez-Sjoberg, Menlo Park, CA (US);

Hung-Ta Wang, Tuscaloosa, AL (US);

Peidong Yang, Kensington, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/06 (2006.01); H01J 49/04 (2006.01); G01N 30/60 (2006.01); G01N 30/72 (2006.01); B01L 3/00 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
G01N 30/06 (2013.01); B01L 3/502753 (2013.01); G01N 30/6095 (2013.01); G01N 30/7233 (2013.01); G01N 30/7266 (2013.01); H01J 49/0431 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0803 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0887 (2013.01); G01N 2030/8813 (2013.01);
Abstract

Systems, methods, and apparatus provide integration of microscopic imaging and liquid chromatography-mass spectrometry on a microfluidic device. In one aspect, an apparatus includes a first wafer, a second wafer, and an emitter. The emitter is disposed between the first wafer and the second wafer. The first wafer defines a sample input hole. The first wafer and the second wafer define a first channel, the first channel including a first end and a second end. The first end of the first channel is proximate the sample input hole. The first channel is configured to contain separation media. The second end of the first channel is proximate the emitter.


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