The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Jul. 04, 2014
Fundació Hospital Universitari Vall D'hebron—institut DE Recerca, Barcelona, ES;
Ciber (Centro DE Investigación Biomédica En Red), Madrid, ES;
Roche Diagnòstics S.l., Sant Cugat del Vallès, ES;
Josep Quer, Barcelona, ES;
Francisco Rodríguez, Barcelona, ES;
Josep Gregori, Caldes de Montbui, ES;
Fundacio Hospital Universitari Vall D'Hebron—Institute de Recerca, Barcelona, ES;
Centro de Investigacion Biomedica en Red, Madrid, ES;
Roche Diagnostics S.L., Sant Cugat del Valles, ES;
Abstract
The invention relates to an in vitro method for determining in an isolated sample of a subject the presence of one or more Human Hepatitis C Virus (HCV) sequence variants comprising reverse transcription and amplifying HCV RNAs molecules using specific sets of primers allowing the amplification of the HCV regions named 5'-UTR-Core and NS5B. The method includes an step for purifying the amplified regions and a sequencing step of the amplified fragments. The invention also includes specific oligonucleotides than are used as primers in the method, as well as kits including one or more of these oligonucleotides as sets of primers.