The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Jan. 20, 2014
Applicant:

Sekisui Chemical Co., Ltd., Osaka, JP;

Inventors:

Masahiro Furutani, Tokyo, JP;

Akihiro Uenishi, Tsukuba, JP;

Koichiro Iwasa, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12P 7/18 (2006.01); C12N 9/10 (2006.01); C12N 9/02 (2006.01); C12N 9/88 (2006.01); C12N 9/00 (2006.01); C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/10 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12Y 101/01244 (2013.01); C12Y 401/02043 (2013.01); C12Y 402/03027 (2013.01);
Abstract

An object of the present invention is to provide a series of techniques for producing 1,4-butanediol from methanol or the like. Provided is a recombinant cell prepared by introducing a gene encoding at least one enzyme selected from the group consisting of succinate semialdehyde dehydrogenase, succinyl-CoA synthase, CoA-dependent succinate semialdehyde dehydrogenase, 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyryl-CoA transferase, 4-hydroxybutyryl-CoA reductase, 4-hydroxybutyraldehyde dehydrogenase, and alcohol dehydrogenase, into a host cell which is a methylotroph, wherein the gene is expressed in the host cell, and the recombinant cell is capable of producing 1,4-butanediol from at least one C1 compound selected from the group consisting of methane, methanol, methylamine, formic acid, formaldehyde, and formamide.


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