The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Nov. 29, 2016
Applicants:

Seoul National University R&db Foundation, Seoul, KR;

University of Ulsan, Ulsan, KR;

Korea Institute of Science and Technology, Seoul, KR;

Pharosgen, Seoul, KR;

Inventors:

Youngro Byun, Seoul, KR;

In San Kim, Daegu, KR;

Ahmed Al-Hilal Taslim, Seoul, KR;

Sang-Yoon Kim, Seoul, KR;

Ye Ji Jang, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 31/727 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); C07K 14/705 (2006.01); C12N 15/113 (2010.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
C07K 16/2872 (2013.01); A61K 31/727 (2013.01); A61K 47/554 (2017.08); C07K 14/705 (2013.01); C07K 16/28 (2013.01); C12N 15/113 (2013.01); G01N 33/57492 (2013.01); G01N 33/6893 (2013.01); A61K 39/3955 (2013.01); C07K 16/18 (2013.01); C07K 2317/14 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3515 (2013.01); G01N 2333/705 (2013.01);
Abstract

Described herein are doppel-targeting molecules useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.


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