The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Feb. 14, 2014
Applicant:
Washington University, St. Louis, MO (US);
Inventor:
Douglas Covey, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/566 (2006.01); A61K 31/568 (2006.01); A61K 31/5685 (2006.01); C07J 1/00 (2006.01); C07J 21/00 (2006.01); C07J 15/00 (2006.01); C07J 41/00 (2006.01); C07C 35/42 (2006.01); C07J 13/00 (2006.01); C07J 31/00 (2006.01); C07J 51/00 (2006.01); C07J 61/00 (2006.01); C07J 63/00 (2006.01); C07J 71/00 (2006.01); C07J 75/00 (2006.01); C07C 43/307 (2006.01);
U.S. Cl.
CPC ...
C07J 1/00 (2013.01); C07J 15/005 (2013.01); C07J 21/00 (2013.01); C07J 41/0094 (2013.01); C07C 35/42 (2013.01); C07C 43/307 (2013.01); C07C 2603/26 (2017.05); C07C 2603/40 (2017.05); C07J 13/002 (2013.01); C07J 21/008 (2013.01); C07J 31/006 (2013.01); C07J 51/00 (2013.01); C07J 61/00 (2013.01); C07J 63/008 (2013.01); C07J 71/001 (2013.01); C07J 75/005 (2013.01);
Abstract
The present disclosure is generally directed to neuroactive enantiomeric 15-, 16- and 17-substituted steroids with additional optional substituents at carbons 3, 4, 6, 7, 10 and 13, and pharmaceutically acceptable salts thereof, for use as, for example, modulators for GABA type-A receptors. The present disclosure is further directed to pharmaceutical compositions comprising such compounds.