The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Apr. 16, 2015
Idenix Pharmaceuticals Llc, Cambridge, MA (US);
David Dukhan, Saint Gely du Fesc, FR;
Cyril B. Dousson, Canet, FR;
Gilles Gosselin, Montpellier, FR;
Jean-Laurent Paparin, Vendemian, FR;
Guillaume Brandt, Montpellier, FR;
Rachid Rahali, Saint Laurent des Arbres, FR;
Aurelien Salanson, Montpellier, FR;
François-René Alexandre, Montpellier, FR;
IDENIX PHARMACEUTICALS LLC, Cambridge, MA (US);
Abstract
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 3'-substituted methyl or alkynyl nucleosides of Formula I: (I); or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein Base, PD, R, R, R, Rand Z are as defined herein.