The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Jul. 24, 2017
President and Fellows of Harvard College, Cambridge, MA (US);
Alec Nathanson Flyer, Boston, MA (US);
Hong Myung Lee, Cambridge, MA (US);
Andrew G. Myers, Boston, MA (US);
Cristina Montserrat Nieto-Oberhuber, Cambridge, MA (US);
Matthew D. Shair, Lexington, MA (US);
Chong Si, Allston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention relates to analogs of cortistatin A, J, K, and L, having the general formula: and salts thereof, wherein R, R, R, R, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin A, J, K, and L, and analogs thereof.