IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10202399 B1

PDFFull Text
Date of Patent:
Feb. 12, 2019

Filed:

Dec. 22, 2016

Dihydroxy aromatic heterocyclic compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Takeshi Hondo, Tokyo, JP;

Keita Nakanishi, Tokyo, JP;

Tatsuya Niimi, Tokyo, JP;

Masaichi Warizaya, Tokyo, JP;

Ichiji Namatame, Tokyo, JP;

Katsuya Harada, Tokyo, JP;

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorney:

Finnegan, Henderson, Farabow, Garrett & Dunner LLP

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 213/69 (2006.01); A61K 31/44 (2006.01); C07D 491/056 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61K 31/4412 (2006.01); A61K 31/4418 (2006.01); A61K 31/4427 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/496 (2006.01); A61K 31/50 (2006.01); A61K 31/501 (2006.01); A61K 31/5377 (2006.01); A61K 31/551 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 237/16 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 403/06 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01); C07D 413/10 (2006.01); C07D 417/06 (2006.01); C07D 253/07 (2006.01); C07D 401/10 (2006.01); C07D 405/10 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 491/056 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4412 (2013.01); A61K 31/4418 (2013.01); A61K 31/4427 (2013.01); A61K 31/4433 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/50 (2013.01); A61K 31/501 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 213/69 (2013.01); C07D 237/16 (2013.01); C07D 253/07 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); C07D 405/10 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/06 (2013.01); C07D 409/12 (2013.01); C07D 413/06 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01);
Abstract

Provided is a compound having a D-amino acid oxidase (DAAO) inhibitory action, and useful as, for example, a prophylaxis and/or therapeutic agent for schizophrenia or neuropathic pain. The present inventors have studied a compound that inhibits DAAO, and confirm that a dihydroxy aromatic heterocyclic compound has a DAAO inhibitory action, and completed the present invention. That is, the dihydroxy aromatic heterocyclic compound of the present invention has a good DAAO inhibitory action, and can be used as a prophylaxis and/or therapeutic agent for, for example, schizophrenia or neuropathic pain.

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