The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Jul. 10, 2015
Applicant:
The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);
Inventors:
Dan Theodorescu, Englewood, CO (US);
Michael Fitzpatrick Wempe, Aurora, CO (US);
David Ross, Niwot, CO (US);
Chao Yan, Denver, CO (US);
Phillip Reigan, Denver, CO (US);
Assignee:
The Regents of the University of Colorado, a body corporate, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); A61K 31/4162 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); A61K 31/4162 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods of inhibiting the growth or metastasis of a cancer in a subject by inhibiting a Ral GTPase in the subject, and small molecule inhibitors of Ral GTPases useful in the methods of the invention. Pharmaceutical compositions containing the compounds of the invention, and methods of using the same.