The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Dec. 21, 2015
Applicant:

Takeda Pharmaceutical Company Limited, Chuo-ku, Osaka-shi, Osaka, JP;

Inventors:

Eiji Kimura, Kanagawa, JP;

Yuhei Miyanohana, Kanagawa, JP;

Masaki Ogino, Kanagawa, JP;

Yuta Tanaka, Kanagawa, JP;

Makoto Fushimi, New York, NY (US);

Tomohiro Okawa, Kanagawa, JP;

Yuki Hanya, Tokyo, JP;

Tatsuki Koike, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/437 (2006.01); C07D 487/04 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 25/00 (2018.01); A61P 29/00 (2018.01); C07D 487/04 (2013.01);
Abstract

Provided is a compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and is useful as a prophylactic or therapeutic agent for major depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, (excluding N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(imidazo[1,2-a]pyridin-5-yl)acetamide) or a salt thereof.


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