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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10202374 B1

PDFFull Text
Date of Patent:
Feb. 12, 2019

Filed:

Feb. 16, 2015

6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors

Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:

Ram Asrey Vishwakarma, Jammu, IN;

Sandip Bibishan Bharate, Jammu, IN;

Shashi Bhushan, Jammu, IN;

Rammohan Rao Yadav, Jammu, IN;

Santosh Kumar Guru, Jammu, IN;

Prashant Joshi, Jammu, IN;

Assignee:

COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi, IN;

Attorneys:

John P. White

Cooper & Dunham LLP

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 239/94 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 239/94 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01);
Abstract

The present invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R' are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-α (PI3K-α) inhibitory activity. In addition, the invention relates to methods of using compounds for treating or preventing various cancers such as pancreatic, prostate, breast and melanoma.

Find Patent Forward Citations

Vishwakarma, Ram. (2019). 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors (U.S. Patent No. 10202374). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10202374

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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