The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Mar. 14, 2014
Applicant:
Karyopharm Therapeutics Inc., Newton, MA (US);
Inventors:
Tami Rashal, Ramat Hasharon, IL;
Dilara McCauley, Arlington, MA (US);
Sharon Shacham, Newton, MA (US);
Erkan Baloglu, Stoneham, MA (US);
Assignee:
Karyopharm Therapeutics Inc., Newton, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); A61K 31/4196 (2006.01); C07D 231/12 (2006.01); C07D 233/64 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 249/08 (2006.01); C07D 257/04 (2006.01); C07D 487/10 (2006.01); C07D 207/325 (2006.01); C07D 207/33 (2006.01); C07D 213/50 (2006.01); A61K 31/41 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/41 (2013.01); A61K 31/4196 (2013.01); C07D 207/325 (2013.01); C07D 207/33 (2013.01); C07D 213/50 (2013.01); C07D 231/12 (2013.01); C07D 233/64 (2013.01); C07D 249/08 (2013.01); C07D 257/04 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/12 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 487/10 (2013.01);
Abstract
The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein Ring A, X, R, Rand n are as defined and described herein, in a method for promoting wound healing in a subject.