The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Apr. 17, 2017
Celgene Quanticel Research, Inc., San Diego, CA (US);
Michael John Bennett, San Diego, CA (US);
Juan Manuel Betancort, San Diego, CA (US);
Amogh Boloor, San Diego, CA (US);
Toufike Kanouni, San Diego, CA (US);
Jeffrey Alan Stafford, San Diego, CA (US);
James Marvin Veal, Apex, NC (US);
Michael Brennan Wallace, San Diego, CA (US);
CELGENE QUANTICEL RESEARCH, INC., San Diego, CA (US);
Abstract
The present disclosure relates to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease.