The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Jul. 07, 2017
Applicants:

Genentech, Inc., South San Francisco, CA (US);

Constellation Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

Alexandre Cote, Cambridge, MA (US);

Victor Gehling, Cambridge, MA (US);

Vickie Hsiao-Wei Tsui, South San Francisco, CA (US);

James Richard Jr. Kiefer, South San Francisco, CA (US);

Jun Liang, South San Francisco, CA (US);

Steven Magnuson, South San Francisco, CA (US);

Christopher G. Nasveschuk, Cambridge, MA (US);

F. Anthony Romero, South San Francisco, CA (US);

Alexander M. Taylor, Cambridge, MA (US);

Assignees:

GENENTECH, INC., South San Francisco, CA (US);

CONSTELLATION PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/44 (2006.01); C07D 235/02 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 233/44 (2013.01); C07D 235/02 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 487/08 (2013.01);
Abstract

The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM2b. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.


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