The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Apr. 06, 2017
Applicant:

Ajinomoto Co., Inc., Tokyo, JP;

Inventor:

Shun Kobayashi, Kawasaki, JP;

Assignee:

AJINOMOTO CO., INC., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/02 (2006.01); C07C 231/22 (2006.01); C07C 233/47 (2006.01); A61K 8/44 (2006.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
C07C 231/02 (2013.01); A61K 8/442 (2013.01); A61Q 19/00 (2013.01); C07C 231/22 (2013.01); C07C 233/47 (2013.01);
Abstract

The present invention provides a method of producing an aqueous solution containing bis(N-lauroyl lysine)dicarboxylic acid diamide and/or a salt thereof, and having a pH of 9-11, which includes a first step of reacting N-lauroyl lysine and/or a salt thereof with dicarboxylic acid dichloride in a water solvent having a pH of 12-14 to form bis(N-lauroyl lysine)dicarboxylic acid diamide and/or a salt thereof, a second step of adjusting the aqueous solution obtained in the first step to pH 7.5-8.5, a third step of adding N-lauroyl lysine to the aqueous solution obtained in the second step and filtering the mixture, and a fourth step of adjusting the aqueous solution obtained in the third step to pH 9-11.


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