The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Jul. 20, 2015
Applicant:
Council of Scientific & Industrial Research, New Delhi, IN;
Inventors:
Sandip Bharate, Jammu, IN;
Ajay Kumar, Jammu, IN;
Jaideep Bharate, Jammu, IN;
Prashant Joshi, Jammu, IN;
Abubakar Wani, Jammu, IN;
Ramesh Mudududdla, Jammu, IN;
Rohit Sharma, Jammu, IN;
Ram Vishwakarma, Jammu, IN;
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 205/34 (2006.01); A61K 31/122 (2006.01); C07C 49/743 (2006.01); C07C 49/84 (2006.01); C07D 311/96 (2006.01);
U.S. Cl.
CPC ...
C07C 49/84 (2013.01); A61K 31/122 (2013.01); C07C 49/743 (2013.01); C07C 205/34 (2013.01); C07D 311/96 (2013.01); C07C 2603/56 (2017.05); C07C 2603/70 (2017.05);
Abstract
The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.