The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Oct. 05, 2017
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Tao Yu, Edison, NJ (US);
Yonglian Zhang, Metuchen, NJ (US);
Sherman Tim Waddell, Westfield, NJ (US);
John M. Sanders, Collegeville, PA (US);
Thomas H. Graham, Quincy, MA (US);
Hong Li, Edison, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/00 (2006.01); A61K 31/44 (2006.01); A61K 31/4375 (2006.01); C07D 455/02 (2006.01); A61K 31/427 (2006.01); A61K 31/4402 (2006.01); A61K 31/444 (2006.01); A61K 31/4745 (2006.01); A61K 31/505 (2006.01); A61K 31/513 (2006.01); A61K 31/52 (2006.01); A61K 31/635 (2006.01); A61K 31/675 (2006.01); C07D 455/00 (2006.01); C07D 455/04 (2006.01); C07D 471/14 (2006.01); C07D 491/147 (2006.01); A61K 45/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4375 (2013.01); A61K 31/427 (2013.01); A61K 31/4402 (2013.01); A61K 31/444 (2013.01); A61K 31/4745 (2013.01); A61K 31/505 (2013.01); A61K 31/513 (2013.01); A61K 31/52 (2013.01); A61K 31/635 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 455/00 (2013.01); C07D 455/02 (2013.01); C07D 455/04 (2013.01); C07D 471/14 (2013.01); C07D 491/147 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention relates to Substituted Quinolizine Derivatives of Formula (I): and pharmaceutically acceptable salts or prodrug thereof, wherein X, Y, R, R, R, R, R, Rand Rare as defined herein. The present invention also relates to compositions comprising at least one Substituted Quinolizine Derivative, and methods of using the Substituted Quinolizine Derivatives for treating or preventing HIV infection in a subject.