The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2019
Filed:
Feb. 20, 2018
Applicant:
City of Hope, Duarte, CA (US);
Inventor:
Yun Yen, Arcadia, CA (US);
Assignee:
City of Hope, Duarte, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 33/24 (2006.01); A61K 31/7068 (2006.01); A61K 45/06 (2006.01); A61K 31/337 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61K 31/337 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 45/06 (2013.01);
Abstract
Provided herein are methods of treating cancer in a subject by administering COH29 ((N-(4-(3,4-dihydroxyphenyl)-5-phenylthiazol-2-yl)-3,4-dihydroxybenzamide)). The methods of treating include treating a BRCA1-defective subject, a PARP1 inhibitor-resistant subject or a DNA-damaging anti-cancer agent resistant subject. The methods include treating cancer by administering COH29 and a DNA-damaging anti-cancer agent in a combined synergistic amount.
Yen, Yun. (2019). Treatment of brca1-defective cancer or resistant cancers (U.S. Patent No. 10201530). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10201530
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