The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2019

Filed:

Sep. 12, 2014
Applicant:

Western University of Health Sciences, Pomona, CA (US);

Inventors:

Moses Sing Sum Chow, Chino Hills, CA (US);

Ying Huang, Arcadia, CA (US);

Zhi Jun Wang, Chino Hills, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/365 (2006.01); A61K 31/704 (2006.01); A61K 31/517 (2006.01); A61K 31/337 (2006.01); A61K 45/06 (2006.01); A61K 36/37 (2006.01);
U.S. Cl.
CPC ...
A61K 31/365 (2013.01); A61K 31/337 (2013.01); A61K 31/517 (2013.01); A61K 31/704 (2013.01); A61K 36/37 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention provides compositions comprising wilforlide A for overcoming drug resistance in cancer therapy, particularly in the treatment of cancers which have exhibited resistance to treatment by chemotherapeutic drugs. Methods and compositions for treating a cancer are disclosed. The method administers to a patient in need thereof a combination of wilforlide A and a chemotherapeutic drug. Wilforlide A and chemotherapeutic drug are administered in a combined amount effective to treat the cancer. The cancer being treated is at least in part resistant to treatment by the chemotherapeutic drug alone.


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