The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Dec. 29, 2017
Applicants:

Sanaria Inc., Rockville, MD (US);

Antigen Discovery, Inc., Irvine, CA (US);

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Inventors:

Philip Felgner, Irvine, CA (US);

Stephen L. Hoffman, Rockville, MD (US);

Robert Seder, Bethesda, MD (US);

Joseph J. Campo, Jr., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); G01N 33/68 (2006.01); A61K 39/015 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); A61K 39/015 (2013.01); G01N 33/56905 (2013.01); A61K 2039/521 (2013.01); A61K 2039/522 (2013.01); A61K 2039/54 (2013.01); G01N 2333/445 (2013.01); G01N 2469/20 (2013.01); Y02A 50/58 (2018.01);
Abstract

Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected againstcaused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against-caused malaria.


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