The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jan. 16, 2018
Applicant:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Inventors:
Anthony Conway, Richmond, CA (US);
Gregory J. Cost, Richmond, CA (US);
Russell Dekelver, Richmond, CA (US);
Edward J. Rebar, Richmond, CA (US);
Andreas Reik, Richmond, CA (US);
Fyodor Urnov, Richmond, CA (US);
Jianbin Wang, Richmond, CA (US);
H. Steve Zhang, Richmond, CA (US);
Assignee:
Sangamo Therapeutics, Inc., Richmond, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C12N 15/11 (2006.01); C07K 2/00 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 2/00 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/90 (2013.01); C12N 15/902 (2013.01); C07K 2319/81 (2013.01); C12N 2320/30 (2013.01); C12Y 301/21004 (2013.01);
Abstract
Methods and compositions comprising a CRISPR/Cas nuclease that cleaves a T cell receptor (TCR) gene and/or human leukocyte (HLA) gene, the nuclease comprising a cleavage domain and a single guide RNA that binds to a target site in the TCR and/or HLA gene.