The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jul. 11, 2017
Applicants:
Niketa A. Patel, Land O' Lakes, FL (US);
Ghattas El Bassit, Tampa, FL (US);
Inventors:
Niketa A. Patel, Land O' Lakes, FL (US);
Ghattas El Bassit, Tampa, FL (US);
Assignees:
University of South Florida, Tampa, FL (US);
The United States of America as Represented by the Department of Veterens Affairs, Washington, DC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C07K 16/28 (2006.01); A61K 38/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0667 (2013.01); A61K 38/1825 (2013.01); C07K 16/2896 (2013.01); A61K 2039/545 (2013.01); C12N 2501/727 (2013.01); C12N 2506/1384 (2013.01);
Abstract
A method of reprogramming omental adipose cells to a subcutaneous-like lineage is presented herein. The method comprises exposing omental adipose cells to a small molecule such as Basic Fibroblast Growth Factor (bFGF); TRC105; long noncoding RNAs (lncRNAs) MALAT1, GAS5, linc-VLDLR; transcription factors Sox15, Oct4, KLF4, Nanog, Sal4, BMI1; or combinations thereof.