The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Aug. 20, 2014
Applicant:
Lek Pharmaceuticals D.d., Ljubljana, SI;
Inventor:
Tanja Ficko Trcek, Ljubljana, SI;
Assignee:
LEK PHARMACEUTICALS D.D., Ljubljana, SK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0018 (2013.01); C07K 16/241 (2013.01); C12N 2500/05 (2013.01); C12N 2500/20 (2013.01); C12N 2500/22 (2013.01);
Abstract
The present invention is related to a cell culture medium for reducing the C-terminal heterogeneity of a polypeptide expressed in cell-culture, wherein the medium comprises at least one essential trace element in an effective amount, and to a cell culture process for reducing C-terminal heterogeneity of a protein, in which process an essential trace element is used.