The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Nov. 17, 2014
Applicants:

Alan L. Epstein, Pasadena, CA (US);

Peisheng HU, Covina, CA (US);

Inventors:

Alan L. Epstein, Pasadena, CA (US);

Peisheng Hu, Covina, CA (US);

John Ohlfest, Roseville, MN (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 39/00 (2006.01); C07K 14/575 (2006.01); A61K 39/39 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); C07K 14/575 (2013.01); C07K 14/70575 (2013.01); A61K 38/00 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55561 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract

Provided is an isolated recombinant polypeptide comprising an immunoglobulin domain and a canine OX40L extracellular domain polypeptide fragment or a biological equivalent thereof and compositions comprising: an isolated recombinant polypeptide comprising an immunoglobulin domain and a canine OX40L extracellular domain polypeptide fragment; and a pharmaceutically acceptable carrier. Also provided are methods for treating or ameliorating the symptoms of cancer in a canine comprising administering an effective amount of the isolated recombinant polypeptide of the disclosure and/or a composition of the disclosure to a canine in need thereof.


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