The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jun. 23, 2015
Applicant:
Dompé Farmaceutici S.p.a., Milan, IT;
Inventors:
Andrea Aramini, L'Aquila, IT;
Gianluca Bianchini, L'Aquila, IT;
Laura Brandolini, L'Aquila, IT;
Andrea Beccari, Gignano di L'Aquila, IT;
Samuele Lillini, Chiaravalle, IT;
Giuseppe Nano, Scoppito, IT;
Assignee:
DOMPÉ FARMACEUTICI S.P.A., Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/34 (2006.01); C07D 417/04 (2006.01); C07D 263/42 (2006.01);
U.S. Cl.
CPC ...
C07D 277/34 (2013.01); C07D 263/42 (2013.01); C07D 417/04 (2013.01);
Abstract
The invention relates to compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I). Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold induced and/or exacerbated respiratory disorders and urological disorders.