The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
May. 26, 2016
Applicant:
Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;
Inventors:
Assignee:
Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); C07D 215/36 (2006.01); A61P 3/00 (2006.01);
U.S. Cl.
CPC ...
C07D 215/36 (2013.01); A61K 31/47 (2013.01); A61P 3/00 (2018.01); C07B 2200/13 (2013.01);
Abstract
Provided are a sodium salt of a uric acid transporter inhibitor and a crystalline form thereof, In particular, provided are a uric acid transporter (URAT1) inhibitor 1-((6-bromo-quinoline-4-yl)thio)cyclobutyl sodium formate (the compound of formula (I)), a crystal form I, and preparation method thereof. The obtained crystal form I of the compound of formula (I) has a good crystal form stability and chemical stability, and the crystallization solvent used has a low toxicity and low residue, and can be better used in clinical treatment.