The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Jul. 24, 2015
Applicant:

Fudan University, Shanghai, CN;

Inventors:

Deyong Ye, Shanghai, CN;

Yali Li, Shanghai, CN;

Lu Zhou, Shanghai, CN;

Penghui Wang, Shanghai, CN;

Yong Chu, Shanghai, CN;

Haojun Gong, Shanghai, CN;

Qi Huang, Shanghai, CN;

Yan Chen, Shanghai, CN;

Zhikuan Zhang, Shanghai, CN;

Assignee:

FUDAN UNIVERSITY, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/75 (2006.01); A61K 31/4406 (2006.01); A61K 31/505 (2006.01); A61K 31/5377 (2006.01); C07D 239/42 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); A61K 31/4406 (2013.01); A61K 31/505 (2013.01); A61K 31/5377 (2013.01); C07D 239/42 (2013.01);
Abstract

2-alkoxy benzene formyl arylamine compounds and their pharmaceutical salts are disclosed. The compounds can act as sphingomyelin synthase (SMS) inhibitors to treat diseases caused by abnormal increasing of sphingomyelin (SM). The pharmaceutically acceptable salts and pharmaceutical compositions of the compounds are used as active ingredients in drugs which can prevent and cure diseases caused by SM level abnormal increase. These diseases include atherosclerosis, fatty liver, obesity, type diabetes, and other metabolic syndromes.


Find Patent Forward Citations

Loading…