The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Nov. 20, 2017
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.l.a. China, Beijing, CN;
Song Li, Beijing, CN;
Junhai Xiao, Beijing, CN;
Lili Wang, Beijing, CN;
Long Long, Beijing, CN;
Wei Li, Beijing, CN;
Haoming Luo, Beijing, CN;
Feifei Li, Beijing, CN;
Wu Zhong, Beijing, CN;
Zhibing Zheng, Beijing, CN;
Yunde Xie, Beijing, CN;
Xingzhou Li, Beijing, CN;
Xinbo Zhou, Beijing, CN;
Xiaokui Wang, Beijing, CN;
Ruiyuan Cao, Beijing, CN;
Abstract
The present invention pertains to the field of pharmaceutical chemicals, and relates to a substituted acethydrazide derivative, preparation method and use thereof; preferably, relates to a compound of Formula I or a pharmaceutically acceptable salt thereof. The compound of the present invention or a pharmaceutically acceptable salt thereof can effectively inhibit proline hydroxylase, stabilize HIF-α, particularly HIF-1α, and has potency in the manufacture of a medicament for treatment and/or prophylaxis and/or adjuvant therapy of anemia, acute ischemic reperfusion injury.