The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Jan. 07, 2015
Applicant:

Hackensack University Medical Center, Hackensack, NJ (US);

Inventors:

K. Stephen Suh, Hackensack, NJ (US);

Sreeja Sarojini, Ridgewood, NJ (US);

Mehmet Tuna, Hackensack, NJ (US);

Joseph Barbiere, Hackensack, NJ (US);

Alois M. Ndlovu, Hackensack, NJ (US);

Andrew L. Pecora, Hackensack, NJ (US);

Anthony Ingenito, Hackensack, NJ (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2006.01); A61K 31/353 (2006.01); A61K 31/337 (2006.01); A61K 31/365 (2006.01);
U.S. Cl.
CPC ...
A61N 5/1077 (2013.01); A61K 31/337 (2013.01); A61K 31/353 (2013.01); A61K 31/365 (2013.01); A61N 5/1031 (2013.01); A61N 2005/1098 (2013.01);
Abstract

The described invention provides methods for irradiating skin cancer cells, such as melanoma cells, at a high radiation rate (e.g., of 2,400 mu/min) and a modest total dose (e.g., of 0.5 Gy) to treat skin cancer or induce apoptosis in skin cancer cells. The radiation may be administered in a plurality of treatments and used in conjunction with chemotherapy.


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