The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jul. 29, 2016
Applicant:
Korea University Research and Business Foundation, Seoul, KR;
Inventors:
Jae-Hong Seo, Gwacheon-si, KR;
Chang-Ill Ban, Pohang-si, KR;
Hun-Ho Jo, Busan, KR;
Ji-Young Kim, Seoul, KR;
Eun-Hye Oh, Seoul, KR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 47/54 (2017.01); A61K 31/5365 (2006.01); C12N 15/115 (2010.01); A61P 31/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/549 (2017.08); A61K 31/5365 (2013.01); A61P 31/00 (2018.01); C07H 21/04 (2013.01); C12N 15/115 (2013.01);
Abstract
This invention relates to a complex for cancer cell chemotherapy and, more particularly, to an AGTR1 aptamer-anticancer drug complex for chemotherapy of cancer cells, which includes a nucleic acid aptamer specifically binding to AGTR1 and an anticancer drug linked with the nucleic acid aptamer, so that AGTR1-positive (overexpressed) breast cancer cells are selectively targeted and killed.