The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Aug. 11, 2015
Applicant:

Albany Medical College, Albany, NY (US);

Inventors:

Patricia Grasso, Schenectady, NY (US);

Zachary Novakovic, Erie, PA (US);

Assignee:

ALBANY MEDICAL COLLEGE, Albany, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/22 (2006.01); A61K 38/10 (2006.01); A61K 9/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2264 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 9/08 (2013.01); A61K 38/00 (2013.01);
Abstract

A pharmaceutical compound for the treatment of obesity related disorder that is a conjugate of myristic acid and a leptin-related peptide. Preferably, the leptin-related peptide is OB3 that has been D-substituted at Leu-4. The resulting conjugate significantly improved the pharmacokinetic profile of the leptin-related peptide by extending its half-life from less than one hour to as long as twenty-eight hours, depending on the route of delivery, increasing uptake, reducing the rate of plasma clearance, and enabling the minimal effective dose to be reduced several fold.


Find Patent Forward Citations

Grasso, Patricia. (2019). Myristoylated leptin-related peptides and uses thereof (U.S. Patent No. 10195254). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10195254

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…