The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jun. 29, 2012
Applicant:
Kathrin Schwager, Zurich, CH;
Inventor:
Kathrin Schwager, Zurich, CH;
Assignee:
PHILOGEN S.P.A., Siena, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 47/68 (2017.01); A61K 49/00 (2006.01); C07K 14/55 (2006.01); C07K 16/18 (2006.01); C07K 14/525 (2006.01);
U.S. Cl.
CPC ...
A61K 38/191 (2013.01); A61K 38/2013 (2013.01); A61K 47/6813 (2017.08); A61K 47/6843 (2017.08); A61K 47/6851 (2017.08); A61K 49/00 (2013.01); C07K 14/525 (2013.01); C07K 14/55 (2013.01); C07K 16/18 (2013.01); A61K 38/00 (2013.01); C07K 2317/622 (2013.01); C07K 2319/33 (2013.01);
Abstract
Methods and compositions for treating tumors, especially skin tumors, by locally administering single doses of tumor necrosis factor alpha (TNFα) and interleukin-2 (IL2) at the tumor site, where the TNFα and IL2 are delivered as immunoconjugates comprising an antibody targeted to a splice isoform of an extracellular matrix component such as fibronectin.