The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jul. 29, 2015
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Huaixiang Hao, Malden, MA (US);
Xizhong Huang, Southborough, MA (US);
Angela Tam, Randolph, MA (US);
Shailaja Kasibhatla, San Diego, CA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/53 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); A61K 31/53 (2013.01); C07D 401/14 (2013.01); C07D 487/04 (2013.01);
Abstract
The present disclosure relates to pharmaceutical products comprising a combination of (i) a MET inhibitor which is INC280 or a pharmaceutically acceptable salt or hydrate thereof and (ii) an EGFR inhibitor described herein, which are jointly active in the treatment of proliferative diseases, corresponding pharmaceutical formulations, uses, methods, processes, commercial packages and related embodiments.