The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Oct. 24, 2012
Applicants:
Signalchem Lifesciences Corporation, Richmond, CA;
British Columbia Cancer Agency, Vancouver, CA;
Inventors:
Assignees:
SIGNALCHEM LIFESCIENCES CORPORATION, Richmond, CA;
BRITISH COLUMBIA CANCER AGENCY BRANCH, Vancouver, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/63 (2006.01); G01N 33/50 (2006.01); A61K 31/337 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/337 (2013.01); A61K 31/63 (2013.01); A61K 31/7048 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); G01N 33/5023 (2013.01); G01N 33/5073 (2013.01); G01N 33/57484 (2013.01); G01N 33/57492 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present disclosure provides methods for detecting the presence of a cancer stem cell and their use in cancer prognosis, evaluating risk of cancer metastasis, identifying or validating drug candidates, and determining treatment efficacy. It also provides kits useful for detecting the presence of cancer stem cells as well as methods of treating cancer using CAIX inhibitors.