The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Sep. 24, 2014
Applicant:

Institute of Biophysics, Chinese Academy of Sciences, Beijing, CN;

Inventors:

Xiyun Yan, Beijing, CN;

Kelong Fan, Beijing, CN;

Minmin Liang, Beijing, CN;

Fei Wang, Beijing, CN;

Demin Duan, Beijing, CN;

Dexi Zhang, Beijing, CN;

Jing Feng, Beijing, CN;

Dongling Yang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/70 (2006.01); A61K 47/42 (2017.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/51 (2013.01); A61K 31/70 (2013.01); A61K 47/42 (2013.01); A61K 47/64 (2017.08); A61K 47/6925 (2017.08);
Abstract

The present disclosure relates to a tumor-targeted drug delivery system, comprising a tumor-targeted drug carrier and a tumor-treating drug, wherein the tumor-targeted drug carrier comprises full heavy-chain human ferritin. The present disclosure also relates to a method for preparing the tumor-targeted drug delivery system comprising: depolymerizing a polymerized full heavy-chain human ferritin; adding a tumor-treating drug to the depolymerized full heavy-chain human ferritin so as to bind the tumor-treating drug to the depolymerized full heavy-chain human ferritin; and re-polymerizing the depolymerized full heavy-chain human ferritin bound with the tumor-treating drug to form a nanoparticle.


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