The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jul. 11, 2014
Applicant:
Sinai Health System, Toronto, CA;
Inventors:
Assignee:
Sinai Health System, Toronto, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/44 (2006.01); C12N 5/00 (2006.01); A61L 27/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/12 (2006.01);
U.S. Cl.
CPC ...
A61F 2/442 (2013.01); A61L 27/12 (2013.01); A61L 27/18 (2013.01); A61L 27/3608 (2013.01); A61L 27/3612 (2013.01); A61L 27/3817 (2013.01); A61L 27/3856 (2013.01); A61L 27/3895 (2013.01); C12N 5/0068 (2013.01); A61F 2002/4435 (2013.01); A61F 2002/4445 (2013.01); A61F 2002/4495 (2013.01); A61L 2430/38 (2013.01);
Abstract
The disclosure relates to an intervertebral disc implant comprising a first construct comprising a continuous layer of nucleus pulposus (NP) tissue directly or indirectly on and integrated with a substrate, and a second construct surrounding the first construct comprising one or more continuous layers of annulus fibrosus (AF) tissue on and adherent to a scaffold, wherein the AF tissue, which is composed of single or multiple adherent layers, is integrated with the NP tissue. The disclosure also relates to methods of preparing the multi-tissue intervertebral disc and using the intervertebral disc as an implant.