The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jan. 30, 2018
Medibeacon Inc., St. Louis, MO (US);
Jennifer Keating, Mountain View, CA (US);
Kimberly Shultz, Mountain View, CA (US);
Kate Bechtel, Pleasant Hill, CA (US);
Edward Solomon, Menlo Park, CA (US);
MediBeacon Inc., St. Louis, MO (US);
Abstract
A method of monitoring a time-varying fluorescence emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is disclosed that includes providing at least two measurements obtained from a patient before and after administration of the fluorescent agent that includes an Flrsignal detected adjacent to the medium by a filtered light detector during illumination of the medium by excitatory-wavelength light, and at least one DR signal selected from: a DRDR, and DRsignal. The method further includes identifying a post-equilibration portion of the measurement data set and transforming each Flrsignal within the post-equilibration portion of the measurement data set to an IFsignal representing a detected fluorescence intensity emitted solely by the fluorescent agent from within the medium. The disclosed method includes removing the effects of leak-through of excitation-level light and removing the effects of autofluorescence from the Flrsignal.