The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2019
Filed:
Jun. 22, 2018
Applicant:
Ivana Ledesma, Philadelphia, PA (US);
Inventor:
Ralph Zuckerman, Philadelphia, PA (US);
Assignee:
CELLVIEW IMAGING INC., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); A61B 5/00 (2006.01); A61B 5/1455 (2006.01); G01N 21/64 (2006.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0071 (2013.01); A61B 5/1455 (2013.01); A61B 5/14546 (2013.01); A61B 5/14555 (2013.01); A61B 5/14556 (2013.01); A61B 5/4842 (2013.01); A61B 5/7246 (2013.01); A61B 5/7278 (2013.01); G01N 21/645 (2013.01); G01N 21/6445 (2013.01); G01N 2021/6484 (2013.01); G01N 2201/0683 (2013.01); G01N 2201/12 (2013.01);
Abstract
A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating the emission of fluorescence, due to one or more endogenous fluorophors in the tissue. Fluorescence anisotropy is then calculated. Such measurements of fluorescence anisotropy are then used to assess the functional status of the tissue, and to identify the existence and severity of disease states. Such assessment can be made by comparing a fluorescence anisotropy profile with a known profile of a control.