The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2019

Filed:

Oct. 30, 2015
Applicant:

Aquabounty Technologies, Inc., Maynard, MA (US);

Inventors:

Xavier Lauth, San Diego, CA (US);

John T. Buchanan, San Diego, CA (US);

Assignee:

AquaBounty Technologies, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); C12N 15/85 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0275 (2013.01); C07K 14/4747 (2013.01); C12N 15/8509 (2013.01); A01K 2207/05 (2013.01); A01K 2217/052 (2013.01); A01K 2217/206 (2013.01); A01K 2227/40 (2013.01); A01K 2267/03 (2013.01); C12N 2800/80 (2013.01); Y02A 90/40 (2018.01);
Abstract

The present invention provides Maternal Sterility Constructs (MSC) and methods of producing sterile progeny lacking germ cells. Female fish carrying the MSC transgene will give rise to a sterile generation, as the MSC specifically eliminates Progenitor Germ Cells (PGCs) of her progeny. These females are called lineage ending females. Male fish carrying the MSC transgene, however, give rise to fertile progeny (assuming the male is not derived from an MSC-transgenic female). Thus, MSC transgenic males can be used to propagate the transgenic line. The invention can be advantageously applied to provide effective population control and improve culture performance of farmed species, such as fish.


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