The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Oct. 26, 2011
Charles J. Vaske, Santa Cruz, CA (US);
Stephen C. Benz, Santa Cruz, CA (US);
Joshua M. Stuart, Santa Cruz, CA (US);
David Haussler, Santa Cruz, CA (US);
Charles J. Vaske, Santa Cruz, CA (US);
Stephen C. Benz, Santa Cruz, CA (US);
Joshua M. Stuart, Santa Cruz, CA (US);
David Haussler, Santa Cruz, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A method of generating a dynamic pathway map (DPM) is provided. The method includes accessing a model database that stores a probabilistic pathway model that comprises a plurality of pathway elements, a first number of the plurality of pathway elements are cross-correlated and assigned an influence level for at least one pathway on the basis of known attributes, a second number of the plurality of pathway elements are cross-correlated and assigned an influence level for at least one pathway on the basis of assumed attributes. The method includes measuring a patient sample to identify measured attributes of the patient sample and using a plurality of the measured attributes of the patient sample, via an analysis engine, to modify the probabilistic pathway model to obtain the DPM, wherein the DPM has reference pathway activity information for a particular pathway, the reference pathway indicating deviations from the probabilistic pathway model.