The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Apr. 13, 2012
Alexey G. Katrukha, Turku, FI;
Alexander B. Postnikov, Moscow, RU;
Tatiana I. Smolyanova, Moscow region, RU;
Alexey V. Kharitonov, Moscow, RU;
Natalia N. Tamm, Moscow, RU;
Alexey G. Katrukha, Turku, FI;
Alexander B. Postnikov, Moscow, RU;
Tatiana I. Smolyanova, Moscow region, RU;
Alexey V. Kharitonov, Moscow, RU;
Natalia N. Tamm, Moscow, RU;
HYTEST LTD., Turku, FI;
Abstract
The present invention describes the method for determining the risk of future major adverse cardiovascular events, which comprises detection proteolytic fragments of IGFBP-4 or IGFBP-5 (insulin-like growth factor binding protein 4 or insulin-like growth factor binding protein 5) in patients' blood. The present invention provides antibodies and immunoas-says, suitable for specific measurement of proteolytic fragments of IGFBPs. In current invention the IGFBP fragments are suggested to be utilized as blood biomarkers for the risk prediction of major adverse cardiovascular events (MACE).