The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Dec. 19, 2016
Applicant:
Biomadison, Inc., Del Mar, CA (US);
Inventors:
Ward C. Tucker, Monona, WI (US);
Timothy M. Piazza, McFarland, WI (US);
Assignee:
BIOMADISON, INC., Del Mar, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01); A47C 15/00 (2006.01); G01N 21/64 (2006.01); C12Q 1/6897 (2018.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); A47C 15/006 (2013.01); C12Q 1/37 (2013.01); C12Q 1/6897 (2013.01); G01N 21/6408 (2013.01); G01N 21/6428 (2013.01); G01N 2333/33 (2013.01);
Abstract
Methods and compositions are provided where a transfected cell that produces a hybrid protein with a reporter-containing portion and atoxin cleavage site is contacted with atoxin in media having a reduced sodium concentration, thereby increasing the sensitivity. Such media can also be used in combination with elevated cell culture temperatures. Kits that include such media and atoxin are also described.